Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Marion Mafham

Marion Mafham

Contact information


marion.mafham@ndph.ox.ac.uk


+44 (0)1865 743743

Marion Mafham

Professor of Medicine and Clinical Trials, Heart Studies Group

  • Professor of Medicine and Clinical Trials, Oxford Population Health, University of Oxford
  • Honorary Consultant Nephrologist, Oxford University Hospitals NHS Foundation Trust

Marion Mafham is a Professor of Medicine and Clinical Trials working in the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) at Oxford Population Health.

Her work aims to improve health by generating reliable randomised evidence about the effects of interventions to treat and prevent common causes of death and disability, focusing on diabetes, cardiovascular and kidney diseases.

She pioneers new trial methods to design large-scale streamlined randomised trials that produce reliable answers, including the use of healthcare systems data in clinical trials and direct-to-participant designs. Her recent clinical trials work includes the mail-based ASCEND study in 15,480 participants with diabetes, the ongoing 15,000 participant ORION-4 study in cardiovascular disease and she co-leads the ASCEND PLUS trial of oral semaglutide in type 2 diabetes. She led the data linkage team for the RECOVERY trial assessing potential hospital treatments for COVID-19. Her research also uses healthcare systems data to generate real time insights into the impact of COVID-19 on NHS care pathways.

She studied medicine at the University of Edinburgh (1992-1998) and completed an MD thesis at the CTSU (2003-2006). After completing her specialist training in Nephrology she returned to CTSU in 2013.